Vectors for Human ABCB11

Gene Information

  • Offical Gene Symbol ABCB11
  • Species Human ( Homo sapiens )
  • Offical Full Name ATP binding cassette subfamily B member 11
  • Other Aliases ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP
  • Other Desigations bile salt export pump; ABC member 16, MDR/TAP subfamily; ATP-binding cassette sub-family B member 11; ATP-binding cassette, sub-family B (MDR/TAP), member 11; progressive familial intrahepatic cholestasis 2; sister p-glycoprotein
  • Gene Type protein-coding
  • Summary
    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 8647
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC

Popular Vector Designs for Human ABCB11(These vectors can be made quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ABCB11 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  EGFP/Puro From $159
Human ABCB11 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  EGFP:T2A:Puro From $159
Human ABCB11 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  EGFP From $159
Human ABCB11 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  EGFP From $159
Human ABCB11 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  EGFP/Puro From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ABCB11 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  EGFP:T2A:Puro $99
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Human ABCB11 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  EGFP $99
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Human ABCB11 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  EGFP $99
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Human ABCB11 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  EGFP:T2A:Puro $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ABCB11 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  EGFP/Puro $99
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Human ABCB11 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Puro $99
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Human ABCB11 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   EGFP $239
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