Vectors for Human ADGRB1

Gene Information

  • Offical Gene Symbol ADGRB1
  • Species Human ( Homo sapiens )
  • Offical Full Name adhesion G protein-coupled receptor B1
  • Other Aliases BAI1; GDAIF
  • Other Desigations adhesion G protein-coupled receptor B1; brain-specific angiogenesis inhibitor 1
  • Gene Type protein-coding
  • Summary
    Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one \'functional\' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 575
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC

Popular Vector Designs for Human ADGRB1(These vectors can be made quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ADGRB1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  EGFP/Puro From $159
Human ADGRB1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  EGFP:T2A:Puro From $159
Human ADGRB1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  EGFP From $159
Human ADGRB1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  EGFP From $159
Human ADGRB1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  EGFP/Puro From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ADGRB1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  EGFP:T2A:Puro $99
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Human ADGRB1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  EGFP $99
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Human ADGRB1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  EGFP $99
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Human ADGRB1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  EGFP:T2A:Puro $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ADGRB1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  EGFP/Puro $99
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Human ADGRB1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Puro $99
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Human ADGRB1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   EGFP $239
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