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Vectors for Human AFP

Gene Information

  • Offical Gene Symbol AFP
  • Species Human (Homo sapiens)
  • Offical Full Name alpha fetoprotein
  • Other Aliases AFPD; FETA; HPAFP
  • Other Desigations alpha-fetoprotein; alpha-1-fetoprotein; alpha-fetoglobulin
  • Gene Type protein-coding
  • Summary
    This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Oct 2019]
  • NCBI Gene ID 174
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human AFP(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human AFP expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human AFP expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human AFP expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human AFP expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human AFP expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human AFP shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
View Vector 
Human AFP shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
View Vector 
Human AFP shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human AFP shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human AFP CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
View Vector 
Human AFP CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
View Vector 
Human AFP CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
View Vector 

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