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Vectors for Human AKR7L

Gene Information

  • Offical Gene Symbol AKR7L
  • Species Human (Homo sapiens)
  • Offical Full Name aldo-keto reductase family 7 like (gene/pseudogene)
  • Other Aliases AFAR3; AFB1-AR 3; AFB1-AR3; AKR7A4
  • Other Desigations aflatoxin B1 aldehyde reductase member 4; AFB1 aldehyde reductase 3; aldo-keto reductase family 7 pseudogene; aldo-keto reductase family 7-like; aldoketoreductase 7-like
  • Gene Type protein-coding
  • Summary
    This gene is one of three aldo-keto reductase genes that are present in a cluster on the p arm of chromosome 1. The encoded proteins are involved in the reduction of the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. It has been speculated that this family member encodes a selenoprotein, which includes a selenocysteine (Sec) residue in lieu of a UGA translational termination codon. However, there is no evidence that such a protein is produced in vivo. The alternative interpretation is that this family member is a segregating pseudogene, where some individuals have an allele that encodes a functional enzyme, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Feb 2017] Annotation information: Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.
  • NCBI Gene ID 246181
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human AKR7L(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human AKR7L expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human AKR7L expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human AKR7L expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human AKR7L expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human AKR7L expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human AKR7L shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human AKR7L shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human AKR7L shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human AKR7L shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human AKR7L CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human AKR7L CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human AKR7L CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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