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Vectors for Human APEH

Gene Information

  • Offical Gene Symbol APEH
  • Species Human (Homo sapiens)
  • Offical Full Name acylaminoacyl-peptide hydrolase
  • Other Aliases AARE; ACPH; APH; D3F15S2; D3S48E; DNF15S2; OPH
  • Other Desigations acylamino-acid-releasing enzyme; N-acylaminoacyl-peptide hydrolase; acyl-peptide hydrolase; acylaminoacyl-peptidase; oxidized protein hydrolase
  • Gene Type protein-coding
  • Summary
    This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 327
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human APEH(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human APEH expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human APEH expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human APEH expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human APEH expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human APEH expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human APEH shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human APEH shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human APEH shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human APEH shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human APEH CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human APEH CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human APEH CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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