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Vectors for Human APH1B

Gene Information

  • Offical Gene Symbol APH1B
  • Species Human (Homo sapiens)
  • Offical Full Name aph-1 homolog B, gamma-secretase subunit
  • Other Aliases APH-1B; PRO1328; PSFL; TAAV688; aph-1beta
  • Other Desigations gamma-secretase subunit APH-1B; APH1B gamma secretase subunit; anterior pharynx defective 1 homolog B
  • Gene Type protein-coding
  • Summary
    This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. [provided by RefSeq, Sep 2011]
  • NCBI Gene ID 83464
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human APH1B(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human APH1B expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human APH1B expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human APH1B expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human APH1B expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human APH1B expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human APH1B shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human APH1B shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human APH1B shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human APH1B shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human APH1B CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human APH1B CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human APH1B CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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