Vectors for Human APOH

Gene Information

  • Offical Gene Symbol APOH
  • Species Human (Homo sapiens)
  • Offical Full Name apolipoprotein H
  • Other Aliases B2G1; B2GP1; BG
  • Other Desigations beta-2-glycoprotein 1; APC inhibitor; B2GPI; activated protein C-binding protein; anticardiolipin cofactor; apo-H; apolipoprotein H (beta-2-glycoprotein I); beta(2)GPI; epididymis secretory sperm binding protein
  • Gene Type protein-coding
  • Summary
    Apolipoprotein H, also known as beta-2-glycoprotein I, is a component of circulating plasma lipoproteins. It has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, hemostasis, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome (APS). The anti-beta (2) glycoprotein I antibodies from APS patients, mediate inhibition of activated protein C which has anticoagulant properties. Because beta-2-GPI is the main autoantigen in patients with APS, the disruption of this pathway by autoantibodies may be an important mechanism for thrombosis in patients with APS.[provided by RefSeq, Dec 2019]
  • NCBI Gene ID 350
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human APOH(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human APOH expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human APOH expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human APOH expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human APOH expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human APOH expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human APOH shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human APOH shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human APOH shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human APOH shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human APOH CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human APOH CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human APOH CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
View Vector 

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