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Vectors for Human ARHGAP35

Gene Information

  • Offical Gene Symbol ARHGAP35
  • Species Human (Homo sapiens)
  • Offical Full Name Rho GTPase activating protein 35
  • Other Aliases GRF-1; GRLF1; P190-A; P190A; p190ARhoGAP; p190RhoGAP
  • Other Desigations rho GTPase-activating protein 35; glucocorticoid receptor DNA-binding factor 1; glucocorticoid receptor repression factor 1; rho GAP p190A
  • Gene Type protein-coding
  • Summary
    The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 2909
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human ARHGAP35(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ARHGAP35 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human ARHGAP35 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human ARHGAP35 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human ARHGAP35 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human ARHGAP35 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ARHGAP35 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human ARHGAP35 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human ARHGAP35 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human ARHGAP35 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ARHGAP35 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human ARHGAP35 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human ARHGAP35 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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