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Vectors for Human ARHGEF12

Gene Information

  • Offical Gene Symbol ARHGEF12
  • Species Human (Homo sapiens)
  • Offical Full Name Rho guanine nucleotide exchange factor 12
  • Other Aliases LARG; PRO2792
  • Other Desigations rho guanine nucleotide exchange factor 12; KMT2A/ARHGEF12 fusion protein; Rho guanine nucleotide exchange factor (GEF) 12; leukemia-associated RhoGEF; leukemia-associated rho guanine nucleotide exchange factor
  • Gene Type protein-coding
  • Summary
    Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
  • NCBI Gene ID 23365
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human ARHGEF12(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ARHGEF12 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human ARHGEF12 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human ARHGEF12 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human ARHGEF12 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human ARHGEF12 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ARHGEF12 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human ARHGEF12 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human ARHGEF12 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human ARHGEF12 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ARHGEF12 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human ARHGEF12 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human ARHGEF12 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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