Vectors for Human ATP2A2

Gene Information

  • Offical Gene Symbol ATP2A2
  • Species Human (Homo sapiens)
  • Offical Full Name ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
  • Other Aliases ATP2B; DAR; DD; SERCA2
  • Other Desigations sarcoplasmic/endoplasmic reticulum calcium ATPase 2; ATPase Ca++ transporting cardiac muscle slow twitch 2; ATPase, Ca++ dependent, slow-twitch, cardiac muscle-2; SR Ca(2+)-ATPase 2; calcium pump 2; cardiac Ca2+ ATPase; endoplasmic reticulum class 1/2 Ca(2+) ATPase
  • Gene Type protein-coding
  • Summary
    This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of the skeletal muscle. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Other types of mutations in this gene have been associated with various forms of muscular dystrophies. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2019]
  • NCBI Gene ID 488
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human ATP2A2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ATP2A2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human ATP2A2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human ATP2A2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human ATP2A2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human ATP2A2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ATP2A2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human ATP2A2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human ATP2A2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human ATP2A2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ATP2A2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human ATP2A2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human ATP2A2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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