Vectors for Human ATP2B4

Gene Information

  • Offical Gene Symbol ATP2B4
  • Species Human (Homo sapiens)
  • Offical Full Name ATPase plasma membrane Ca2+ transporting 4
  • Other Aliases ATP2B2; MXRA1; PMCA4; PMCA4b; PMCA4x
  • Other Desigations plasma membrane calcium-transporting ATPase 4; ATPase, Ca++ transporting, plasma membrane 4; matrix-remodeling-associated protein 1; sarcolemmal calcium pump
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 493
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human ATP2B4(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ATP2B4 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human ATP2B4 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human ATP2B4 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human ATP2B4 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human ATP2B4 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ATP2B4 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human ATP2B4 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human ATP2B4 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human ATP2B4 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human ATP2B4 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human ATP2B4 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human ATP2B4 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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