Vectors for Human BCAR4

Gene Information

Offical Gene Symbol BCAR4
Species Human (Homo sapiens)
Offical Full Name breast cancer anti-estrogen resistance 4
Other Aliases -
Other Desigations breast cancer anti-estrogen resistance 4 (non-protein coding); breast cancer antiestrogen resistance 4 protein
Gene Type ncRNA
Summary
This gene produces a spliced long non-coding RNA (lncRNA) that has been implicated in breast cancer metastasis. It was originally identified in a screen for genes responsible for the development of resistance to anti-estrogens in breast cancer cells. It is thought that release of CCL21 enables this lncRNA to bind to the SNIP1 and PNUTS transcription factors, thereby activating a non-canonical GLI-dependent hedgehog signaling pathway that promotes cancer cell migration and invasion. A similar gene in cow expresses a protein in mature oocytes and preimplantation embryos. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2015]
NCBI Gene ID 400500
RefSeq Transcript
NR_024049.1; NR_024050.1; NR_131216.1; NR_131217.1; NR_131222.1
RefSeq Protein
-; -; -; -; -
External Links NCBI | OMIM | Ensembl | HGNC | UCSC Genome Browser View
View ORF sequence of this gene »

No vectors are found in our database for this gene. We may introduce vectors for this gene in the future.

Use this option to design your vector using our online platform.

You can request cloning & virus packaging services for your vector here.

Use this option to ask our scientists to design your vector for free.

You can also submit other service inquires here, including: