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Vectors for Human BIRC7

Gene Information

  • Offical Gene Symbol BIRC7
  • Species Human (Homo sapiens)
  • Offical Full Name baculoviral IAP repeat containing 7
  • Other Aliases KIAP; LIVIN; ML-IAP; MLIAP; RNF50
  • Other Desigations baculoviral IAP repeat-containing protein 7; RING finger protein 50; RING-type E3 ubiquitin transferase BIRC7; kidney inhibitor of apoptosis protein; livin inhibitor of apoptosis; melanoma inhibitor of apoptosis protein
  • Gene Type protein-coding
  • Summary
    This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jul 2013]
  • NCBI Gene ID 79444
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human BIRC7(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human BIRC7 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human BIRC7 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human BIRC7 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human BIRC7 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human BIRC7 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human BIRC7 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human BIRC7 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human BIRC7 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human BIRC7 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human BIRC7 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human BIRC7 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human BIRC7 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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