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Vectors for Human BLM

Gene Information

  • Offical Gene Symbol BLM
  • Species Human (Homo sapiens)
  • Offical Full Name BLM RecQ like helicase
  • Other Aliases BS; MGRISCE1; RECQ2; RECQL2; RECQL3
  • Other Desigations recQ-like DNA helicase BLM; Bloom syndrome RecQ like helicase; Bloom syndrome, RecQ helicase-like; DNA helicase, RecQ-like type 2; bloom syndrome protein; recQ protein-like 3
  • Gene Type protein-coding
  • Summary
    The Bloom syndrome is an autosomal recessive disorder characterized by growth deficiency, microcephaly and immunodeficiency among others. It is caused by homozygous or compound heterozygous mutation in the gene encoding DNA helicase RecQ protein on chromosome 15q26. This Bloom-associated helicase unwinds a variety of DNA substrates including Holliday junction, and is involved in several pathways contributing to the maintenance of genome stability. Identification of pathogenic Bloom variants is required for heterozygote testing in at-risk families. [provided by RefSeq, May 2020]
  • NCBI Gene ID 641
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human BLM(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human BLM expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human BLM expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human BLM expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human BLM expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human BLM expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human BLM shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
View Vector 
Human BLM shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
View Vector 
Human BLM shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human BLM shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human BLM CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
View Vector 
Human BLM CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human BLM CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
View Vector 

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