Vectors for Human CAND1

Gene Information

  • Offical Gene Symbol CAND1
  • Species Human (Homo sapiens)
  • Offical Full Name cullin associated and neddylation dissociated 1
  • Other Aliases TIP120; TIP120A
  • Other Desigations cullin-associated NEDD8-dissociated protein 1; TBP-interacting protein of 120 kDa A; p120 CAND1
  • Gene Type protein-coding
  • Summary
    This gene encodes an essential regulator of Cullin-RING ubiquitin ligases, which are in involved in ubiquitinylation of proteins degraded by the Ub proteasome system. The encoded protein binds to unneddylated cullin-RING box protein complexes and acts as an inhibitor of cullin neddylation and of Skp1, cullin, and F box ubiquitin ligase complex assembly and activity. In mammalian cell culture, this protein predominantly localizes to the cytoplasm. Knockdown of this gene in preadipocytes results in blocked adipogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]
  • NCBI Gene ID 55832
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human CAND1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CAND1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human CAND1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human CAND1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human CAND1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human CAND1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CAND1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human CAND1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human CAND1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human CAND1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CAND1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human CAND1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human CAND1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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