Human CCND2 (Gene ID: 894) vectors - Lentivirus, AAV, shRNA & CRISPR I VectorBuilder

Gene Information

Offical Gene Symbol CCND2
Species Human (Homo sapiens)
Offical Full Name cyclin D2
Other Aliases KIAK0002; MPPH3
Other Desigations G1/S-specific cyclin-D2
Gene Type protein-coding
Summary
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK4 or CDK6 and functions as a regulatory subunit of the complex, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. Mutations in this gene are associated with megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3 (MPPH3). [provided by RefSeq, Sep 2014]
NCBI Gene ID 894
RefSeq Transcript
NM_001759.4
RefSeq Protein
NP_001750.1
External Links NCBI | OMIM | Ensembl | HGNC | UCSC Genome Browser View
View ORF sequence of this gene »

Vector Description	Vector Type	Price
Human CCND2 expression regular plasmid vector	Mammalian Gene Expression Vector Guide	From $189
Human CCND2 expression lentivirus vector	Mammalian Gene Expression Lentiviral Vector Guide	From $189
Human CCND2 expression adenovirus vector	Mammalian Gene Expression Adenoviral Vector Guide	From $189
Human CCND2 expression AAV vector	Mammalian Gene Expression AAV Vector Guide	From $189
Human CCND2 expression PiggyBac vector	Mammalian Gene Expression PiggyBac Vector Guide	From $189

Vector Description	Vector Type	Price
Human CCND2 shRNA lentivirus vector	Mammalian shRNA Knockdown Lentiviral Vector Guide	$149	View Vector
Human CCND2 shRNA adenovirus vector	Mammalian shRNA Knockdown Adenoviral Vector Guide	$299	View Vector
Human CCND2 shRNA AAV vector	Mammalian shRNA Knockdown AAV Vector Guide	$149	View Vector
Human CCND2 shRNA PiggyBac vector	Mammalian shRNA Knockdown PiggyBac Vector Guide	$149	View Vector

Vector Description	Vector Type	Price
Human CCND2 CRISPR regular plasmid vector	Mammalian CRISPR Vector (Single gRNA) Guide	$149	View Vector
Human CCND2 CRISPR lentivirus vector	Mammalian CRISPR Lentiviral Vector (Single gRNA) Guide	$149	View Vector
Human CCND2 CRISPR adenovirus vector	Mammalian CRISPR Adenoviral Vector (Single gRNA) Guide	$299	View Vector

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