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Vectors for Human CDC45

Gene Information

  • Offical Gene Symbol CDC45
  • Species Human (Homo sapiens)
  • Offical Full Name cell division cycle 45
  • Other Aliases CDC45L; CDC45L2; MGORS7; PORC-PI-1
  • Other Desigations cell division control protein 45 homolog; CDC45 cell division cycle 45 homolog; CDC45 cell division cycle 45-like; CDC45-related protein; cell division cycle 45 homolog; cell division cycle 45-like 2; human CDC45
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
  • NCBI Gene ID 8318
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human CDC45(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CDC45 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human CDC45 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human CDC45 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human CDC45 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human CDC45 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CDC45 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human CDC45 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human CDC45 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human CDC45 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CDC45 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human CDC45 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human CDC45 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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