Vectors for Human CDK8

Gene Information

  • Offical Gene Symbol CDK8
  • Species Human (Homo sapiens)
  • Offical Full Name cyclin dependent kinase 8
  • Other Aliases IDDHBA; K35
  • Other Desigations cyclin-dependent kinase 8; CDK8 protein kinase; cell division protein kinase 8; mediator complex subunit CDK8; mediator of RNA polymerase II transcription subunit CDK8; protein kinase K35
  • Gene Type protein-coding
  • Summary
    This gene encodes a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit, cyclin C, are components of the Mediator transcriptional regulatory complex, involved in both transcriptional activation and repression by phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II. This kinase regulates transcription by targeting the cyclin-dependent kinase 7 subunits of the general transcription initiation factor IIH, thus providing a link between the Mediator complex and the basal transcription machinery. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
  • NCBI Gene ID 1024
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human CDK8(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CDK8 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human CDK8 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human CDK8 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human CDK8 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human CDK8 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CDK8 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human CDK8 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human CDK8 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human CDK8 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CDK8 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human CDK8 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human CDK8 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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