Vectors for Human CLPB

Gene Information

  • Offical Gene Symbol CLPB
  • Species Human (Homo sapiens)
  • Offical Full Name caseinolytic mitochondrial matrix peptidase chaperone subunit B
  • Other Aliases ANKCLB; HSP78; MEGCANN; MGCA7; MGCA7A; SCN9; SKD3
  • Other Desigations caseinolytic peptidase B protein homolog; ClpB caseinolytic peptidase B homolog; ClpB homolog, mitochondrial AAA ATPase chaperonin; ankyrin-repeat containing bacterial clp fusion; suppressor of potassium transport defect 3; testicular secretory protein Li 11
  • Gene Type protein-coding
  • Summary
    This gene belongs to the ATP-ases associated with diverse cellular activities (AAA+) superfamily. Members of this superfamily form ring-shaped homo-hexamers and have highly conserved ATPase domains that are involved in various processes including DNA replication, protein degradation and reactivation of misfolded proteins. All members of this family hydrolyze ATP through their AAA+ domains and use the energy generated through ATP hydrolysis to exert mechanical force on their substrates. In addition to an AAA+ domain, the protein encoded by this gene contains a C-terminal D2 domain, which is characteristic of the AAA+ subfamily of Caseinolytic peptidases to which this protein belongs. It cooperates with Hsp70 in the disaggregation of protein aggregates. Allelic variants of this gene are associated with 3-methylglutaconic aciduria, which causes cataracts and neutropenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
  • NCBI Gene ID 81570
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human CLPB(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CLPB expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human CLPB expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human CLPB expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human CLPB expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human CLPB expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CLPB shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Human CLPB shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $269
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Human CLPB shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human CLPB shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CLPB CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Human CLPB CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $99
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Human CLPB CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $269
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