Vectors for Human CNTNAP2

Gene Information

  • Offical Gene Symbol CNTNAP2
  • Species Human (Homo sapiens)
  • Offical Full Name contactin associated protein 2
  • Other Aliases AUTS15; CASPR2; CDFE; NRXN4; PTHSL1
  • Other Desigations contactin-associated protein-like 2; cell recognition molecule Caspr2; contactin associated protein like 2; homolog of Drosophila neurexin IV
  • Gene Type protein-coding
  • Summary
    This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2, a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and intellectual disability. [provided by RefSeq, Jul 2017]
  • NCBI Gene ID 26047
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human CNTNAP2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CNTNAP2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human CNTNAP2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human CNTNAP2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human CNTNAP2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human CNTNAP2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CNTNAP2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Human CNTNAP2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $269
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Human CNTNAP2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human CNTNAP2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CNTNAP2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Human CNTNAP2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $99
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Human CNTNAP2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $269
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