Vectors for Human COPS5

Gene Information

  • Offical Gene Symbol COPS5
  • Species Human (Homo sapiens)
  • Offical Full Name COP9 signalosome subunit 5
  • Other Aliases CSN5; JAB1; MOV-34; SGN5
  • Other Desigations COP9 signalosome complex subunit 5; 38 kDa Mov34 homolog; COP9 constitutive photomorphogenic homolog subunit 5; jun activation domain-binding protein 1; signalosome subunit 5; testis secretory sperm-binding protein Li 231m
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 10987
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human COPS5(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human COPS5 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human COPS5 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human COPS5 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human COPS5 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human COPS5 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human COPS5 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Human COPS5 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $269
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Human COPS5 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human COPS5 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human COPS5 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Human COPS5 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $99
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Human COPS5 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $269
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