Vectors for Human CRB1

Gene Information

  • Offical Gene Symbol CRB1
  • Species Human (Homo sapiens)
  • Offical Full Name crumbs cell polarity complex component 1
  • Other Aliases CRB1-A; CRB1-B; CRB1-C; LCA8; RP12
  • Other Desigations protein crumbs homolog 1; crumbs 1, cell polarity complex component; crumbs family member 1, photoreceptor morphogenesis associated
  • Gene Type protein-coding
  • Summary
    This gene encodes a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternate splicing results in multiple transcript variants, some protein coding and some non-protein coding.[provided by RefSeq, Apr 2012]
  • NCBI Gene ID 23418
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human CRB1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CRB1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human CRB1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human CRB1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human CRB1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human CRB1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CRB1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Human CRB1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $269
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Human CRB1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human CRB1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CRB1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Human CRB1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $99
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Human CRB1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $269
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