Vectors for Human CRYBA1

Gene Information

  • Offical Gene Symbol CRYBA1
  • Species Human (Homo sapiens)
  • Offical Full Name crystallin beta A1
  • Other Aliases CRYB1; CTRCT10
  • Other Desigations beta-crystallin A3; beta crystallin A3 chain transcript CN; beta crystallin A3 chain transcript LAM; beta crystallin A3 chain transcript PS; beta crystallin A3 chain transcript TC; crystallin beta A3/A1; crystallin, beta A3; eye lens structural protein; truncated beta crystallin A3/A1 chain; truncated beta-crystallin A3
  • Gene Type protein-coding
  • Summary
    Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a single mRNA, the latter protein is 17 aa shorter than crystallin, beta A3 and is generated by use of an alternate translation initiation site. Deletion of exons 3 and 4 causes the autosomal dominant disease \'zonular cataract with sutural opacities\'. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 1411
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human CRYBA1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CRYBA1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human CRYBA1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human CRYBA1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human CRYBA1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human CRYBA1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CRYBA1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Human CRYBA1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $269
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Human CRYBA1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human CRYBA1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CRYBA1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Human CRYBA1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $99
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Human CRYBA1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $269
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