Vectors for Human CXCR6

Gene Information

  • Offical Gene Symbol CXCR6
  • Species Human (Homo sapiens)
  • Offical Full Name C-X-C motif chemokine receptor 6
  • Other Aliases BONZO; CD186; CDw186; STRL33; TYMSTR
  • Other Desigations C-X-C chemokine receptor type 6; G protein-coupled receptor; G-protein coupled receptor STRL33; G-protein coupled receptor bonzo; chemokine (C-X-C motif) receptor 6
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the CXC chemokine receptor family. This family also includes CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, and CXCR7. This gene, which maps to the chemokine receptor gene cluster, is expressed in several T lymphocyte subsets and bone marrow stromal cells. The encoded protein and its exclusive ligand, chemokine ligand 16 (CCL16), are part of a signalling pathway that regulates T lymphocyte migration to various peripheral tissues (the liver, spleen red pulp, intestine, lungs, and skin) and promotes cell-cell interaction with dendritic cells and fibroblastic reticular cells. CXCR6/CCL16 also controls the localization of resident memory T lymphocytes to different compartments of the lung and maintains airway resident memory T lymphocytes, which are an important first line of defense against respiratory pathogens. The encoded protein serves as an entry coreceptor used by HIV-1 and SIV to enter target cells, in conjunction with CD4. [provided by RefSeq, Aug 2020]
  • NCBI Gene ID 10663
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human CXCR6(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CXCR6 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human CXCR6 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human CXCR6 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human CXCR6 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human CXCR6 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CXCR6 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Human CXCR6 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $269
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Human CXCR6 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human CXCR6 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human CXCR6 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Human CXCR6 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $99
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Human CXCR6 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $269
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