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Vectors for Human DEFA4

Gene Information

  • Offical Gene Symbol DEFA4
  • Species Human (Homo sapiens)
  • Offical Full Name defensin alpha 4
  • Other Aliases DEF4; HNP-4; HP-4; HP4
  • Other Desigations defensin alpha 4; corticostatin; corticostatin HP-4; defensin, alpha 4, corticostatin; defensin, alpha 4, preproprotein; neutrophil defensin 4
  • Gene Type protein-coding
  • Summary
    Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq, Oct 2014]
  • NCBI Gene ID 1669
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human DEFA4(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DEFA4 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human DEFA4 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human DEFA4 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human DEFA4 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human DEFA4 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DEFA4 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human DEFA4 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human DEFA4 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human DEFA4 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DEFA4 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human DEFA4 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human DEFA4 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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