Vectors for Human DENND5A

Gene Information

  • Offical Gene Symbol DENND5A
  • Species Human (Homo sapiens)
  • Offical Full Name DENN domain containing 5A
  • Other Aliases DEE49; EIEE49; RAB6IP1
  • Other Desigations DENN domain-containing protein 5A; DENN/MADD domain containing 5A; RAB6 interacting protein 1; rab6-interacting protein 1
  • Gene Type protein-coding
  • Summary
    This gene encodes a DENN-domain-containing protein that functions as a RAB-activating guanine nucleotide exchange factor (GEF). This protein catalyzes the conversion of GDP to GTP and thereby converts inactive GDP-bound Rab proteins into their active GTP-bound form. The encoded protein is recruited by RAB6 onto Golgi membranes and is therefore referred to as RAB6-interacting protein 1. This protein binds with RAB39 as well. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene are associated with early infantile epileptic encephalopathy-49. [provided by RefSeq, Feb 2017]
  • NCBI Gene ID 23258
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human DENND5A(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DENND5A expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human DENND5A expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human DENND5A expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human DENND5A expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human DENND5A expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DENND5A shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human DENND5A shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human DENND5A shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human DENND5A shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DENND5A CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human DENND5A CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human DENND5A CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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