Vectors for Human DHFR

Gene Information

  • Offical Gene Symbol DHFR
  • Species Human (Homo sapiens)
  • Offical Full Name dihydrofolate reductase
  • Other Aliases DHFR1; DHFRP1; DYR
  • Other Desigations dihydrofolate reductase
  • Gene Type protein-coding
  • Summary
    Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014]
  • NCBI Gene ID 1719
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human DHFR(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DHFR expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human DHFR expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human DHFR expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human DHFR expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human DHFR expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DHFR shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
View Vector 
Human DHFR shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
View Vector 
Human DHFR shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
View Vector 
Human DHFR shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DHFR CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
View Vector 
Human DHFR CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human DHFR CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
View Vector 

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