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Vectors for Human DKC1

Gene Information

  • Offical Gene Symbol DKC1
  • Species Human (Homo sapiens)
  • Offical Full Name dyskerin pseudouridine synthase 1
  • Other Aliases CBF5; CHINE1; DKC; DKCX; NAP57; NOLA4; XAP101
  • Other Desigations H/ACA ribonucleoprotein complex subunit DKC1; CBF5 homolog; H/ACA ribonucleoprotein complex subunit 4; dyskeratosis congenita 1, dyskerin; nopp140-associated protein of 57 kDa; nucleolar protein NAP57; nucleolar protein family A member 4; snoRNP protein DKC1
  • Gene Type protein-coding
  • Summary
    This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
  • NCBI Gene ID 1736
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human DKC1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DKC1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human DKC1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human DKC1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human DKC1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human DKC1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DKC1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human DKC1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human DKC1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human DKC1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DKC1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human DKC1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human DKC1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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