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Vectors for Human DPH5

Gene Information

  • Offical Gene Symbol DPH5
  • Species Human (Homo sapiens)
  • Offical Full Name diphthamide biosynthesis 5
  • Other Aliases AD-018; CGI-30; HSPC143; NEDSFF; NPD015
  • Other Desigations diphthine methyl ester synthase; DPH5 homolog; diphthamide biosynthesis methyltransferase; diphthine synthase; protein x 0011
  • Gene Type protein-coding
  • Summary
    This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 51611
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human DPH5(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DPH5 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human DPH5 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human DPH5 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human DPH5 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human DPH5 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DPH5 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human DPH5 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human DPH5 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human DPH5 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human DPH5 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human DPH5 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human DPH5 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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