Click to refer colleagues and get 30% off
  1. Home
  2. Find Popular Vectors
  3. Vectors for Human E2F4

Vectors for Human E2F4

Gene Information

  • Offical Gene Symbol E2F4
  • Species Human (Homo sapiens)
  • Offical Full Name E2F transcription factor 4
  • Other Aliases E2F-4
  • Other Desigations transcription factor E2F4; E2F transcription factor 4, p107/p130-binding; p107/p130-binding protein
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 1874
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human E2F4(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human E2F4 expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human E2F4 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human E2F4 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human E2F4 expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human E2F4 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human E2F4 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human E2F4 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human E2F4 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human E2F4 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human E2F4 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human E2F4 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human E2F4 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

Can’t find desired vectors above? Use options below to obtain custom vectors.

Design My Vector

Use this option to design your vector using our online platform.

You can request cloning & virus packaging services for your vector here.

Request Design Support

Use this option to ask our scientists to design your vector for free.

You can also submit other service inquires here, including:

  • Virus packaging
  • CRISPR targeting
  • BAC modification
  • Library construction
  • Plasmid DNA Preparation
  • RNA preparation
  • Mutagenesis
  • and more...