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Vectors for Human EIF6

Gene Information

  • Offical Gene Symbol EIF6
  • Species Human (Homo sapiens)
  • Offical Full Name eukaryotic translation initiation factor 6
  • Other Aliases CAB; EIF3A; ITGB4BP; b(2)gcn; eIF-6; p27(BBP); p27BBP
  • Other Desigations eukaryotic translation initiation factor 6; B4 integrin interactor; eukaryotic translation initiation factor 3A; p27 beta-4 integrin-binding protein
  • Gene Type protein-coding
  • Summary
    Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
  • NCBI Gene ID 3692
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human EIF6(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human EIF6 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human EIF6 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human EIF6 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human EIF6 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human EIF6 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human EIF6 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human EIF6 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human EIF6 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human EIF6 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human EIF6 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human EIF6 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human EIF6 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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