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Vectors for Human G6PC1

Gene Information

  • Offical Gene Symbol G6PC1
  • Species Human (Homo sapiens)
  • Offical Full Name glucose-6-phosphatase catalytic subunit 1
  • Other Aliases G6PC; G6PT; G6Pase; GSD1; GSD1a
  • Other Desigations glucose-6-phosphatase catalytic subunit 1; G-6-Pase; G6Pase-alpha; glucose-6-phosphatase alpha
  • Gene Type protein-coding
  • Summary
    Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.[provided by RefSeq, Feb 2011]
  • NCBI Gene ID 2538
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human G6PC1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human G6PC1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human G6PC1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human G6PC1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human G6PC1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human G6PC1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human G6PC1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human G6PC1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human G6PC1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human G6PC1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human G6PC1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human G6PC1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human G6PC1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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