Human GCSH (Gene ID: 2653) vectors - Lentivirus, AAV, shRNA & CRISPR I VectorBuilder

Gene Information

Offical Gene Symbol GCSH
Species Human (Homo sapiens)
Offical Full Name glycine cleavage system protein H
Other Aliases GCE; MMDS7; NKH
Other Desigations glycine cleavage system H protein, mitochondrial; glycine cleavage system protein H (aminomethyl carrier); lipoic acid-containing protein; mitochondrial glycine cleavage system H-protein
Gene Type protein-coding
Summary
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.[provided by RefSeq, Jan 2010]
NCBI Gene ID 2653
RefSeq Transcript
NM_004483.5
RefSeq Protein
NP_004474.2
External Links NCBI | OMIM | Ensembl | HGNC | UCSC Genome Browser View
View ORF sequence of this gene »

Vector Description	Vector Type	Price
Human GCSH expression regular plasmid vector	Mammalian Gene Expression Vector Guide	From $189
Human GCSH expression lentivirus vector	Mammalian Gene Expression Lentiviral Vector Guide	From $189
Human GCSH expression adenovirus vector	Mammalian Gene Expression Adenoviral Vector Guide	From $189
Human GCSH expression AAV vector	Mammalian Gene Expression AAV Vector Guide	From $189
Human GCSH expression PiggyBac vector	Mammalian Gene Expression PiggyBac Vector Guide	From $189

Vector Description	Vector Type	Price
Human GCSH shRNA lentivirus vector	Mammalian shRNA Knockdown Lentiviral Vector Guide	$149	View Vector
Human GCSH shRNA adenovirus vector	Mammalian shRNA Knockdown Adenoviral Vector Guide	$299	View Vector
Human GCSH shRNA AAV vector	Mammalian shRNA Knockdown AAV Vector Guide	$149	View Vector
Human GCSH shRNA PiggyBac vector	Mammalian shRNA Knockdown PiggyBac Vector Guide	$149	View Vector

Vector Description	Vector Type	Price
Human GCSH CRISPR regular plasmid vector	Mammalian CRISPR Vector (Single gRNA) Guide	$149	View Vector
Human GCSH CRISPR lentivirus vector	Mammalian CRISPR Lentiviral Vector (Single gRNA) Guide	$149	View Vector
Human GCSH CRISPR adenovirus vector	Mammalian CRISPR Adenoviral Vector (Single gRNA) Guide	$299	View Vector

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