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Vectors for Human GLE1

Gene Information

  • Offical Gene Symbol GLE1
  • Species Human (Homo sapiens)
  • Offical Full Name GLE1 RNA export mediator
  • Other Aliases CAAHC; CAAHD; GLE1L; LCCS; LCCS1; hGLE1
  • Other Desigations mRNA export factor GLE1; GLE1 RNA export mediator homolog; GLE1-like protein; GLE1-like, RNA export mediator; nucleoporin GLE1
  • Gene Type protein-coding
  • Summary
    This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 2733
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human GLE1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human GLE1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human GLE1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human GLE1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human GLE1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human GLE1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human GLE1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human GLE1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human GLE1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human GLE1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human GLE1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human GLE1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human GLE1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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