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Vectors for Human HARS2

Gene Information

  • Offical Gene Symbol HARS2
  • Species Human (Homo sapiens)
  • Offical Full Name histidyl-tRNA synthetase 2, mitochondrial
  • Other Aliases HARSL; HARSR; HO3; HisRS; PRLTS2
  • Other Desigations histidine--tRNA ligase, mitochondrial; HARS-related; histidine tRNA ligase 2, mitochondrial (putative); histidine translase; histidine-tRNA ligase homolog; histidyl-tRNA synthetase 2, mitochondrial (putative); histidyl-tRNA synthetase 2, mitochondrial, hisRS; probable histidine--tRNA ligase, mitochondrial; probable histidyl-tRNA synthetase, mitochondrial
  • Gene Type protein-coding
  • Summary
    Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes likely share a bidirectional promoter. Mutations in this gene are associated with the pathogenesis of Perrault syndrome, which involves ovarian dysgenesis and sensorineural hearing loss. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
  • NCBI Gene ID 23438
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human HARS2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human HARS2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human HARS2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human HARS2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human HARS2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human HARS2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human HARS2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human HARS2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human HARS2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human HARS2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human HARS2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human HARS2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human HARS2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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