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Vectors for Human HJV

Gene Information

  • Offical Gene Symbol HJV
  • Species Human (Homo sapiens)
  • Offical Full Name hemojuvelin BMP co-receptor
  • Other Aliases HFE2; HFE2A; JH; RGMC
  • Other Desigations hemojuvelin; RGM domain family member C; haemojuvelin; hemochromatosis type 2 (juvenile); hemochromatosis type 2 protein; hemojuvelin BMP coreceptor; repulsive guidance molecule c
  • Gene Type protein-coding
  • Summary
    The product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Two uORFs in the 5\' UTR negatively regulate the expression and activity of the encoded protein. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30. [provided by RefSeq, Oct 2015]
  • NCBI Gene ID 148738
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human HJV(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human HJV expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human HJV expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human HJV expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human HJV expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human HJV expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human HJV shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human HJV shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human HJV shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human HJV shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human HJV CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human HJV CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human HJV CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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