Vectors for Human LIFR

Gene Information

  • Offical Gene Symbol LIFR
  • Species Human (Homo sapiens)
  • Offical Full Name LIF receptor subunit alpha
  • Other Aliases CD118; LIF-R; SJS2; STWS; SWS
  • Other Desigations leukemia inhibitory factor receptor; CD118 antigen; LIF receptor alpha; leukemia inhibitory factor receptor alpha
  • Gene Type protein-coding
  • Summary
    This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2018]
  • NCBI Gene ID 3977
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human LIFR(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human LIFR expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human LIFR expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human LIFR expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human LIFR expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human LIFR expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human LIFR shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human LIFR shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human LIFR shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human LIFR shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human LIFR CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human LIFR CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human LIFR CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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