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Vectors for Human MAPK10

Gene Information

  • Offical Gene Symbol MAPK10
  • Species Human (Homo sapiens)
  • Offical Full Name mitogen-activated protein kinase 10
  • Other Aliases JNK3; JNK3A; PRKM10; SAPK1b; p493F12; p54bSAPK
  • Other Desigations mitogen-activated protein kinase 10; JNK3 alpha protein kinase; MAP kinase 10; MAP kinase p49 3F12; c-Jun N-terminal kinase 3; stress activated protein kinase beta; stress-activated protein kinase 1b; stress-activated protein kinase JNK3
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals, and thus are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system, and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]
  • NCBI Gene ID 5602
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human MAPK10(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human MAPK10 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human MAPK10 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human MAPK10 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human MAPK10 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human MAPK10 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human MAPK10 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human MAPK10 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human MAPK10 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human MAPK10 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human MAPK10 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human MAPK10 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human MAPK10 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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