Vectors for Human MASP1

Gene Information

  • Offical Gene Symbol MASP1
  • Species Human (Homo sapiens)
  • Offical Full Name MBL associated serine protease 1
  • Other Aliases 3MC1; CRARF; CRARF1; MAP-1; MAP1; MASP; MASP-3; MASP3; MAp44; PRSS5; RaRF
  • Other Desigations mannan-binding lectin serine protease 1; C4/C2 activating component of Ra-reactive factor; Ra-reactive factor serine protease p100; complement factor MASP-3; complement-activating component of Ra-reactive factor; mannan binding lectin serine peptidase 1; mannose-associated serine protease 1; mannose-binding lectin-associated serine protease 1; mannose-binding protein-associated serine protease; serine protease 5
  • Gene Type protein-coding
  • Summary
    This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
  • NCBI Gene ID 5648
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human MASP1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human MASP1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human MASP1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human MASP1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human MASP1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human MASP1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human MASP1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human MASP1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human MASP1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human MASP1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human MASP1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human MASP1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human MASP1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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