Vectors for Human MCM10

Gene Information

  • Offical Gene Symbol MCM10
  • Species Human (Homo sapiens)
  • Offical Full Name minichromosome maintenance 10 replication initiation factor
  • Other Aliases CNA43; DNA43; IMD80; PRO2249
  • Other Desigations protein MCM10 homolog; MCM10 minichromosome maintenance deficient 10; homolog of yeast MCM10; hsMCM10; minichromosome maintenance complex component 10
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 55388
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human MCM10(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human MCM10 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human MCM10 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human MCM10 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human MCM10 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human MCM10 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human MCM10 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human MCM10 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human MCM10 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human MCM10 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human MCM10 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human MCM10 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human MCM10 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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