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Vectors for Human MCM3AP

Gene Information

  • Offical Gene Symbol MCM3AP
  • Species Human (Homo sapiens)
  • Offical Full Name minichromosome maintenance complex component 3 associated protein
  • Other Aliases GANP; MAP80; PNRIID; SAC3
  • Other Desigations germinal-center associated nuclear protein; 80 kDa MCM3-associated protein; MCM3 acetylating protein; MCM3 acetyltransferase; MCM3 import protein; MCM3 minichromosome maintenance deficient 3 associated protein; germinal center-associated nuclear protein; germinal-centre associated nuclear protein
  • Gene Type protein-coding
  • Summary
    The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability. [provided by RefSeq, Jan 2014]
  • NCBI Gene ID 8888
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human MCM3AP(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human MCM3AP expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human MCM3AP expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human MCM3AP expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human MCM3AP expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human MCM3AP expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human MCM3AP shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human MCM3AP shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human MCM3AP shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human MCM3AP shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human MCM3AP CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human MCM3AP CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human MCM3AP CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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