Vectors for Human METAP2

Gene Information

  • Offical Gene Symbol METAP2
  • Species Human (Homo sapiens)
  • Offical Full Name methionyl aminopeptidase 2
  • Other Aliases MAP2; MNPEP; p67eIF2
  • Other Desigations methionine aminopeptidase 2; eIF-2-associated p67 homolog; initiation factor 2-associated 67 kDa glycoprotein; peptidase M 2; testicular tissue protein Li 17
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
  • NCBI Gene ID 10988
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human METAP2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human METAP2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human METAP2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human METAP2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human METAP2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human METAP2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human METAP2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human METAP2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human METAP2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human METAP2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human METAP2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human METAP2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human METAP2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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