Vectors for Human NFE4

Gene Information

Offical Gene Symbol NFE4
Species Human (Homo sapiens)
Offical Full Name nuclear factor, erythroid 4
Other Aliases NF-E4
Other Desigations fetal globin activator NF-E4; gamma-globin gene activator; transcription factor NF-E4
Gene Type ncRNA
Summary
The erythroid-specific protein encoded by this gene, and the ubiquitous transcription factor CP2, form the stage selector protein (SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG (CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform (22 kDa) acts as an activator, the short isoform (14 kDa) has been shown to repress gamma-globin gene expression. This gene is located in an intron of the FBXL13 gene on the opposite strand. [provided by RefSeq, Jul 2008]
NCBI Gene ID 58160
RefSeq Transcript
NM_001085386.2
RefSeq Protein
-
External Links NCBI | OMIM | Ensembl | HGNC | UCSC Genome Browser View
View ORF sequence of this gene »

No vectors are found in our database for this gene. We may introduce vectors for this gene in the future.

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