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Vectors for Human NKX2-8

Gene Information

  • Offical Gene Symbol NKX2-8
  • Species Human (Homo sapiens)
  • Offical Full Name NK2 homeobox 8
  • Other Aliases NKX2.8; NKX2H; Nkx2-9
  • Other Desigations homeobox protein Nkx-2.8; NK-2 homolog 8; NK-2 homolog H; NK2 transcription factor related, locus 8; homeobox protein NK-2 homolog H
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects. [provided by RefSeq, Dec 2015]
  • NCBI Gene ID 26257
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human NKX2-8(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human NKX2-8 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human NKX2-8 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human NKX2-8 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human NKX2-8 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human NKX2-8 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human NKX2-8 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human NKX2-8 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human NKX2-8 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human NKX2-8 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human NKX2-8 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human NKX2-8 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human NKX2-8 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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