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Vectors for Human PARN

Gene Information

  • Offical Gene Symbol PARN
  • Species Human (Homo sapiens)
  • Offical Full Name poly(A)-specific ribonuclease
  • Other Aliases DAN; DKCB6; PFBMFT4
  • Other Desigations poly(A)-specific ribonuclease PARN; deadenylating nuclease; deadenylation nuclease; polyadenylate-specific ribonuclease
  • Gene Type protein-coding
  • Summary
    The protein encoded by this gene is a 3\'-exoribonuclease, with similarity to the RNase D family of 3\'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • NCBI Gene ID 5073
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human PARN(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PARN expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human PARN expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human PARN expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human PARN expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human PARN expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PARN shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
View Vector 
Human PARN shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
View Vector 
Human PARN shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
View Vector 
Human PARN shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PARN CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
View Vector 
Human PARN CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human PARN CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
View Vector 

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