Vectors for Human POGLUT1

Gene Information

  • Offical Gene Symbol POGLUT1
  • Species Human (Homo sapiens)
  • Offical Full Name protein O-glucosyltransferase 1
  • Other Aliases C3orf9; CLP46; KDELCL1; KTELC1; LGMD2Z; LGMDR21; MDS010; MDSRP; Rumi; hCLP46
  • Other Desigations protein O-glucosyltransferase 1; 9630046K23Rik; CAP10-like 46 kDa protein; KDELC family like 1; KTEL (Lys-Tyr-Glu-Leu) containing 1; KTEL motif-containing protein 1; O-glucosyltransferase Rumi homolog; hRumi; myelodysplastic syndromes relative protein; protein O-xylosyltransferase POGLUT1; x 010 protein
  • Gene Type protein-coding
  • Summary
    This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
  • NCBI Gene ID 56983
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human POGLUT1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human POGLUT1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human POGLUT1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human POGLUT1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human POGLUT1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human POGLUT1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human POGLUT1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human POGLUT1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human POGLUT1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human POGLUT1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human POGLUT1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human POGLUT1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human POGLUT1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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