Vectors for Human PRKCI

Gene Information

  • Offical Gene Symbol PRKCI
  • Species Human (Homo sapiens)
  • Offical Full Name protein kinase C iota
  • Other Aliases DXS1179E; PKCI; nPKC-iota
  • Other Desigations protein kinase C iota type; PRKC-lambda/iota; aPKC-lambda/iota; atypical protein kinase C-lambda/iota
  • Gene Type protein-coding
  • Summary
    This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 5584
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human PRKCI(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PRKCI expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human PRKCI expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human PRKCI expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human PRKCI expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human PRKCI expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PRKCI shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human PRKCI shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human PRKCI shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human PRKCI shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PRKCI CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human PRKCI CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human PRKCI CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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