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Vectors for Human PRPF8

Gene Information

  • Offical Gene Symbol PRPF8
  • Species Human (Homo sapiens)
  • Offical Full Name pre-mRNA processing factor 8
  • Other Aliases HPRP8; PRP8; PRPC8; RP13; SNRNP220
  • Other Desigations pre-mRNA-processing-splicing factor 8; 220 kDa U5 snRNP-specific protein; PRP8 homolog; PRP8 pre-mRNA processing factor 8 homolog; U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p; apoptosis-regulated protein 1; apoptosis-regulated protein 2; p220; precursor mRNA processing protein; splicing factor Prp8
  • Gene Type protein-coding
  • Summary
    Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 10594
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human PRPF8(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PRPF8 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human PRPF8 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human PRPF8 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human PRPF8 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human PRPF8 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PRPF8 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human PRPF8 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human PRPF8 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human PRPF8 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PRPF8 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human PRPF8 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human PRPF8 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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