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Vectors for Human PRSS12

Gene Information

  • Offical Gene Symbol PRSS12
  • Species Human (Homo sapiens)
  • Offical Full Name serine protease 12
  • Other Aliases BSSP-3; BSSP3; MRT1
  • Other Desigations neurotrypsin; brain-specific serine protease 3; leydin; protease, serine 12; protease, serine, 12 (neurotrypsin, motopsin)
  • Gene Type protein-coding
  • Summary
    This gene encodes a member of the trypsin family of serine proteases and contains a signal peptide, a proline-rich region, a Kringle domain, four scavenger receptor cysteine-rich domains, and a trypsin-like serine protease domain. The protein, sometimes referred to as neurotrypsin or motopsin, is secreted from neuronal cells and localizes to the synaptic cleft. Studies in mice show that this protein cleaves a protein, agrin, that is important for the formation and maintenance of exitatory synapses. Defects in this gene cause a form of autosomal recessive cognitive impairment (MRT1). [provided by RefSeq, Jul 2017]
  • NCBI Gene ID 8492
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human PRSS12(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PRSS12 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human PRSS12 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human PRSS12 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human PRSS12 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human PRSS12 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PRSS12 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
View Vector 
Human PRSS12 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human PRSS12 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human PRSS12 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PRSS12 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
View Vector 
Human PRSS12 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human PRSS12 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
View Vector 

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