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Vectors for Human PTGIS

Gene Information

  • Offical Gene Symbol PTGIS
  • Species Human (Homo sapiens)
  • Offical Full Name prostaglandin I2 synthase
  • Other Aliases CYP8; CYP8A1; PGIS; PTGI
  • Other Desigations prostacyclin synthase; cytochrome P450, family 8, subfamily A, polypeptide 1; hydroperoxy icosatetraenoate dehydratase; prostaglandin I2 (prostacyclin) synthase
  • Gene Type protein-coding
  • Summary
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 5740
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human PTGIS(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PTGIS expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human PTGIS expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human PTGIS expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human PTGIS expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human PTGIS expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PTGIS shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
View Vector 
Human PTGIS shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
View Vector 
Human PTGIS shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
View Vector 
Human PTGIS shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human PTGIS CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
View Vector 
Human PTGIS CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human PTGIS CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
View Vector 

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